What Everyone Must Know About HEMOPHILIA

What Everyone Must Know About HEMOPHILIA:
Hemophilia In hemophilia or hereditary bleeding is a genetic disease (which occurs in parents-to-child) disease, which usually occurs in males and is spread by women. Through today's article you will know what is Hemophilia, what causes it and what are the symptoms of hemophilia and how it can be treated and protected. If a person does not stop bleeding after injury to any person, then this should not be considered a common problem. Because this problem indicates hemophilia. Internal bleeding during hemophilia can damage your organs and tissues and lead to danger.

Hemophilia is a genetic condition. This condition is not curable, but it can be treated to reduce its symptoms and prevent future health complications.

What Everyone Must Know About HEMOPHILIA

What is Hemophilia?
Hemophilia is a rare condition in which blood clots are not properly formed. Hemophilia is a inherited hereditary disease, which affects most men.
People with Hemophilia (Hemophilia) lack a certain protein, which is called clotting factor. There are 13 types of clotting factors (blood clotting factors) that work with platelets in order to prevent bleeding in the area of ​​injury. Platelets are small blood cells that are formed in your bone marrow.
Excessive damage to the coagulation factor leads to bleeding. A spontaneous or internal bleeding can be fatal for life if within an important part of the brain.
Types of Hemophilia:
There are three main types of hemophilia (Hemophilia), Hemophilia A, hemophilia b, and hemophilia C.

Hemophilia A. - This is the most common type of hemophilia, and this disease is caused by a decrease in clotting factor (coagulation factor) VIII. According to the National Heart, Lung (Lung) and Blood Institute (NHLBI), 8 out of 10 people suffering from Hemophilia have Hemophilia A type.

Hemophilia B - Hemophilia B is also called Christmas disease, due to the lack of clotting factor IX in the body.

Hemophilia C - This is a mild form of disease, which is caused due to the lack of clotting factor XI. People with this rare type of hemophilia often do not experience normal bleeding. Hemorrhaging usually happens after very deep injuries or surgeries.

Hemophilia can also be developed after birth, but it is found in very few cases. This type of hemophilia is called "acquisition hemophilia". This hemophilia occurs in people whose immune system produces antibodies. It attacks the antibody clotting factor VIII or IX.

Main Symptoms of Hemophilia:
Depending on the level of clotting factors (blood clotting factors) the symptoms of hemophilia are revealed differently. If there is a decrease in the level of clotting-factor in the body, then bleeding can occur after surgery or trauma (severe injury) in the body. And if there is a decrease in the level of claiting-factor, it can be experienced bleeding easily. And bleeding may also occur in external or internal forms. Symptoms of secretion of hemorrhage include the following factors:
  1. Maximum bleeding with cuts or injuries.
  2. Ambiguous injuries.
  3. Abnormal bleeding after immunization.
  4. Pain in your joints, swelling.
  5. Blue blue marks in the body.
  6. bleeding gums.
  7. Many large or deep injuries occur.
  8. Bleeding in your urine or stool.
  9. Uncertain irritation in infants.
  10. Nose bleeding.
  11. Symptoms of cerebral hemorrhage may include problems like headache, vomiting, lethargy, behavior change, dizziness, vision problems, paralysis and seizures.

Main Causes of Hemophilia:
When the blood flows, the body usually collects blood cells and flows blood in blood cells. All clotting factors in this process contribute to their own. Hemophilia is caused by a reduction in one of these clotting factors.

There are many types of hemophilia that are mostly inherited, for whom the genes are responsive. Hemophilia is more in men, because the gene can be passed from the mother to the son.

Women can be carriers of Hemophilia, but they are not likely to have this disease. To be hemophilia for a girl, there should be an extraordinary gene on one of the X chromosomes, X chromosomes, which is very rare to be found.

Hemophilia Genetic Relations:
Hemophilia is a heritable inherited condition. Hemophilia is caused by an error of gene. This gene determines the body to be formed by the coagulation factor VIII, IX, or XI. These genes are located on the X chromosome.

Women have two X chromosomes. Men have an X and Y chromosome found in men. Men receive a Y chromosome from their mother and a Y chromosome from their father. Whereas, women receive an X chromosome from parents.

Since the genetic defect is the cause of the hemophilia X chromosome, due to which a father can not give this disease to his sons. A female with X-chromosomal, which has a replacement genes, can give those genes as hemophilia disease to their children, men and women.

A woman who holds the X chromosome with the converted genes can give the disease to her children. But she does not have this disease. The reason for this is that there is enough clotting factor in their normal X chromosome to avoid severe bleeding.

Diagnosis of Hemophilia:
  1. Hemophilia is diagnosed through blood test. Depending on the test, the amount of clotting factor (coagulation factor) is measured, taking a sample of the blood of the doctor's victim. Therefore, the severity of the disease based on the results of the blood test is determined as follows:
  2. When a clotting factor in the blood plasma is found between 5 to 40 percent. So this indicates mild hemophilia.
  3. In moderate hemophilia, the level of a clotting factor (coagulation factor) in blood plasma is between 1 to 5 percent.
  4. And when there is less than 1 percent of the clotting factor in the blood plasma, it exhibits severe hemophilia.
  5. Hemophilia is also diagnosed on the basis of a physical examination.

Home remedies of Hemophilia:
Various types of clotting factors are associated with different types of hemophilia. On this basis, following treatment can be done to prevent the symptoms of hemophilia:

Fibrin sealants - These drugs can be applied directly to a wound place to promote clotting and treatment. Fibrin sealants are used in dental treatment too. These medicines can be helpful in treating Hemophilia B.

Desmopressin (DDVP) - In mild hemophilia, this DDAVP hormone stimulates your body to be more clotting factor. This hormone is gradually entered into the body in the form of injections in a vein or in the form of nasal spray. It is very important in the treatment of hemophilia-A.

Vaccinations - If you have hemophilia, you may want to get vaccination against Hepatitis A and B. Because this vaccination reduces the infection of the disease.

First aid for minor cuts - Pressure and bandage (bandage) are usually used to prevent bleeding. Use an ice pack to prevent bleeding in lower lower areas of the skin. Ice pops can be used to reduce minor bleeding in the mouth.

Physical therapy - Signs and symptoms arising from joint damage due to internal bleeding by this therapy can be reduced. When internal bleeding causes serious damage to the body, then surgery may be required.

Clot-protected drugs (anti-fibrinolytics) - These medicines help in preventing blood clots from breaking down.

Hemophilia Complications:
The complications of hemophilia include:
Deep internal bleeding - Hemorrhage in the body's internal muscles causes inflammation in the body organs. Inflammation can suppress veins and cause cramps or pain.

Damage to joints - Internal bleeding also puts too much effect on joints, causing severe and severe pain. If untreated, internal bleeding may cause excessive damage to arthritis or joints.

Infection - People with hemophilia are more likely to get blood transfusion.

Adverse reactions to clotting factor treatment - Some people with hemophilia have bad effects on the body's immune system on the clotting factors used to treat bleeding. When the immune system generates proteins (known as barrier), this protein reduces the treatment of clotting factors and makes the treatment less effective.

Prevention of Hemophilia:
  1. Regular exercise should be done.
  2. Well tooth and mouth should be kept clean.
  3. Some medicines should be avoided, such medicines include: aspirin, non-steroid anti-inflammatory drugs and heparin etc.
  4. Hemophilia should be checked during blood donation or during blood transfusion.
  5. Vaccination should be ensured.
  6. To protect from injuries causing bleeding, one should wear padding. More care is required when participating in sports or more injury activities.

Although there is no successful method of treating hemophilia. But the following methods can be adopted for reducing the risk of excessive bleeding and prevention.

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